by Anneke_e | Sep 6, 2026 | Publication
The three retinoic acid receptors (RARα, β, and γ) have distinct roles, so retinoid-based therapies need isoform-selective compounds. This review by Powała et al. focuses on RARγ, which helps maintain stem cells is overexpressed in many cancers. It describes how...
by Anneke_e | Sep 6, 2026 | Uncategorized
Another eRaDicate secondment has been successfully completed. Our Marie Skłodowska-Curie Doctoral Researcher Giorgia Risso recently spent several weeks at the University of Birmingham, where she worked closely with fellow eRaDicate researcher Linn Dennison. During her...
by Anneke_e | Aug 28, 2026 | Uncategorized
Our PhD researchers Giorgia Risso and Alice Keirle took part in the EMBO|FEBS Lecutre Course “Cancer research: from fundamental insights to clinical application”, held from 17 to 23 August in Spetses, Greece. The course brought together PhD students,...
by Anneke_e | Jul 31, 2026 | Publication
POU1F1 is a transcription factor that can push breast cancer cells toward a cancer stem cell‑like state. When POU1F1 levels are high, the cells produce more IL‑6, which activates the JAK2/STAT3 signaling pathway. This pathway is known for supporting cell survival,...
by Anneke_e | Jul 31, 2026 | Publication
The gastrointestinal tract represents a primary route of daily human exposure to micro- and nanoplastics, yet their behavior within tumor cells remains poorly understood. Brynzak-Schreiber, Schögl et al. investigated the uptake, intracellular distribution, and...
