Advancing the frontiers of breast cancer research – L. Avila et al.

March 27, 2026

Our consortium member, the Endocrine Oncology Group from the University of Santiago de Compostela (Spain), recently published their work in npj Breast Cancer, demonstrating that the POU1F1 transcription factor drives a breast cancer stem cell-like phenotype in the Luminal A subtype of human breast cancer.

The publication can be accessed via the following link: POU1F1 induces cancer stem cell-like traits in breast cancer cells by IL-6/JAK2/STAT3 activation and enrichment of ALDH

Or via the following DOI: 10.1038/s41523-026-00929-w